Inventor

MCLAREN, Earl; MCLAREN, Derek

Publication number

WO2021207822A1

Applicant

MCPHARMA BIOTECH INC.

Abstract

Protein fermentation by the gut microbiome generates a number of metabolites, including the uremic toxins indoxyl sulfate (IS) and p-cresol sulfate (p-CS). RS consumption significantly altered the microbiome while improving several measures of protein fermentation in the gut. The use of RS by those needing to reduce the effects of protein fermentation, for example patients with chronic kidney disease, can be guided by simultaneously measuring changes in select genera in the microbiome