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Effect of cocoa flavanol supplementation for the prevention of cardiovascular disease events: the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial

Authors

 

Howard D Sesso, JoAnn E Manson, Aaron K Aragaki, Pamela M Rist, Lisa G Johnson, Georgina Friedenberg, Trisha Copeland, Allison Clar, Samia Mora, M Vinayaga Moorthy, Ara Sarkissian, William R Carrick, Garnet L Anderson, COSMOS Research Group

 

Abstract

 

Cocoa extract is a source of flavanols that favourably influence vascular risk factors in small and short-term trials, yet effects on clinical cardiovascular events are untested. Cocoa extract supplementation did not significantly reduce total cardiovascular events among older adults.

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