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24 Jan

Epigenetic landscape in blood leukocytes following ketosis and weight loss induced by a very low calorie ketogenic diet (VLCKD) in patients with obesity

by miriam.vendrell
in Artículos científicos – EUT
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Authors

 

Ana B. Crujeiras, Andrea G. Izquierdo, David Primo, Fermin I. Milagro, Ignacio Sajoux, Amalia Jácome, Alfredo Fernandez-Quintela, María P. Portillo, J.Alfredo Martínez, Miguel A. Martinez-Olmos, Daniel de Luis, Felipe F. Casanueva.

 

Abstract

 

The molecular mechanisms underlying the potential health benefits of a ketogenic diet are unknown and could be mediated by epigenetic mechanisms. The beneficial effects of VLCKD therapy on obesity involve a methylome more suggestive of normal weight that could be mainly mediated by the VLCKD-induced ketosis rather than weight loss.

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