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Genome-wide association study of fish oil supplementation on lipid traits in 81,246 individuals reveals new gene-diet interaction loci

Authors

 

Michael Francis, Changwei Li, Yitang Sun, Jingqi Zhou, Xiang Li, J.Thomas Brenna, Kaixiong Ye

 

Abstract

 

Fish oil supplementation is widely used for reducing serum triglycerides (TAGs) but has mixed effects on other circulating cardiovascular biomarkers (…) Our study identifies novel gene-diet interaction effects for four genetic loci, whose effects on blood lipids are modified by fish oil supplementation. These findings highlight the need and possibility for personalized nutrition.

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