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Healthy lifestyle, metabolomics and incident type 2 diabetes in a population-based cohort from Spain

Authors

 

Mario Delgado-Velandia, Vannina Gonzalez-Marrachelli, Arce Domingo-Relloso, Marta Galvez-Fernandez, Maria Grau-Perez, Pablo Olmedo, Iñaki Galan, Fernando Rodriguez-Artalejo, Nuria Amigo, Laisa Briongos-Figuero, Josep Redon, Juan Carlos Martin-Escudero, Daniel Monleon-Salvado, Maria Tellez-Plaza & Mercedes Sotos-Prieto

 

Abstract

 

We assessed the association of a composite measure of lifestyle with plasma metabolite profiles and incident type 2 diabetes.The HLS showed a strong inverse association with incident type 2 diabetes, which was largely explained by plasma metabolites measured years before the clinical diagnosis.

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