04
Dec
Immune response modulation using live biotherapeutics, for conditions such as allergy desensitization
Comments
Inventor
GILBERT Jack A., [US] Daniel van der LELIE [US], Safiyh TAGHAVI [US]
Publication Number
US20200016256A1
Applicant
UNIV CHICAGO, GUSTO GLOBAL LLC
Abstract
Provided herein are compositions (e.g., probiotic, pharmaceutical, etc.) comprising one or more strains of non-Clostridia class bacteria and methods of use thereof for allergen desensitization. In particular, bacteria of bacterial classes such as Negativicutes, Actinobacteria and Bacteroidia support allergen desensitization, for example, by promoting production of metabolites that aid and in desensitization or performing catabolism of food allergens.