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Immune response modulation using live biotherapeutics, for conditions such as allergy desensitization

Inventor

 

GILBERT Jack A., [US] Daniel van der LELIE [US], Safiyh TAGHAVI [US] 

 

Publication Number

 

US20200016256A1 

 

Applicant

 

UNIV CHICAGO, GUSTO GLOBAL LLC 

 

Abstract

 

Provided herein are compositions (e.g., probioticpharmaceutical, etc.) comprising one or more strains of non-Clostridia class bacteria and methods of use thereof for allergen desensitization. In particular, bacteria of bacterial classes such as NegativicutesActinobacteria and Bacteroidia support allergen desensitization, for example, by promoting production of metabolites that aid  and in desensitization or performing catabolism of food allergens. 

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