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Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism

Authors

 

Eugeni Belda, Lise Voland, Valentina Tremaroli, Gwen Falony, Solia Adriouch, Karen E Assmann, Edi Prifti, Judith Aron-Wisnewsky, Jean Debédat et al.

 

Abstract

 

We examined the human gut microbiome’s functional composition in healthy metabolic state and the most severe states of obesity and type 2 diabetes within the MetaCardis cohort. We focused on the role of B vitamins and B7/B8 biotin for regulation of host metabolic state, as these vitamins influence both microbial function and host metabolism.

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