15
Apr
Nutritional modulation of gene expression: might this be of benefit to individuals with Crohn´s disease?
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Author
Lynnette R. Ferguson
Abstract
The incidence of inflammatory bowel diseases (IBD), including Crohn’s disease (CD), is increasing worldwide, especially in young children and adolescents. However, current nutritional advice does not differ from general population guidelines. International collaborative studies have revealed 163 distinct genetic loci affecting susceptibility to IBD, in some of which host–microbe interactions can be seen to play an important role. Certain recognized nutrients, such as vitamin D and long-chain omega-3 PUFAs, may be required at higher than anticipated levels.
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