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TransDiscovery: Discovering Biotransformation from Human Microbiota by Integrating Metagenomic and Metabolomic Data

Autores

 

Donghui Yan, Liu Cao, Muqing Zhou and Hosein Mohimani

 

Abstract

 

Our microbiome affects our health through the products of biochemical reactions catalyzed by microbial enzymes. We present TransDiscovery, a computational algorithm that integrates molecular networks, association networks and knowledge bases of microbial enzymes to discover microbial biotransformations, their substrates, and their products.

 

Resumen del artículo

 

TransDiscovery es una herramienta computacional que aporta información sobre los procesos de biotransformación microbiana (sustratos, productos, enzimas microbianas o redes moleculares implicadas) que tienen lugar gracias a la microbiota intestinal y que tienen impacto en la salud de las personas.

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